CAR T-Cell Therapy

At UMass Memorial Health, you have access to promising new treatment options, such as CAR T-cell therapy.

Chimeric Antigen Receptor T-Cell Therapy: How It Works

CAR T-cell therapy starts by modifying a sample of your T cells. In a laboratory, experts reprogram the cells to produce chimeric antigen receptors. We then put the modified cells back into your body through a vein (infusion). Careful measures are in place throughout this process to ensure safe, high-quality services.

Here’s more about how it works: 

T Cell Collection

We remove blood through a needle in your arm. The blood flows into an apheresis machine, which removes specific blood components (like T cells). The remaining components flow back into your body through a needle in the other arm. 

Infusion

When the modified cells are ready, we admit you to the hospital and deliver them via infusion. Before receiving CAR T cells, you undergo a few days of chemotherapy followed by a few days of rest. You then receive a blood transfusion containing your T cells.

Monitoring

It’s necessary to stay in the hospital after CAR T-cell therapy so we can monitor your response. You may receive medications to prevent or control side effects, such as reactions to CAR T-cells (cytokine release syndrome), infections or fever. Monitoring may last a few days or up to several weeks. 

CAR T-Cell Therapy: Why Choose Us?

Expertise

You receive services from hematologist-oncologists who deliver the best available blood cancer treatments. Our depth of experience with CAR T-cell therapy leads to timely, appropriate care. Our attentive approach makes it possible to manage side effects so you can achieve excellent results.

CAR-T Cell Therapy Research

UMass Memorial is one of the few programs in the region advancing blood cancer treatment through research. We participate in regional and national clinical trials exploring CAR T-cell therapy’s effectiveness for additional cancer types. Find out more about cancer research and clinical trials.

Coordinated Care

CAR T-cell therapy is one of many services that make up your personalized care plan. Hematologist-oncologists may arrange additional treatments before or after CAR T-cell therapy. We also offer comprehensive support from nurse navigators, social workers and palliative medicine doctors. Get more information about cancer resources and support

Get Started

Call 855-UMASS-MD (855-862-7763) to make an appointment with a CAR T-cell therapy.

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