CAR T-Cell Therapy
Our Cancer Locations
Simonds-Sinon Regional Cancer Center
275 Nichols Road,
Fitchburg, 01420 MA
UMass Memorial Medical Center - Memorial Campus Peter H. Levine Ambulatory Center
33 Kendall Street,
Levine Building,
Worcester, 01605 MA
The Cancer Center at Harrington Hospital - Southbridge Campus
55 Sayles Street,
Southbridge, 01550 MA
HealthAlliance-Clinton Hospital - Fitchburg Campus
275 Nichols Road,
Fitchburg, 01420 MA
UMass Memorial Medical Center - University Campus
55 Lake Avenue North,
Worcester, 01655 MA
Chimeric Antigen Receptor T-Cell Therapy: How It Works
CAR T-cell therapy starts by modifying a sample of your T cells. In a laboratory, experts reprogram the cells to produce chimeric antigen receptors. We then put the modified cells back into your body through a vein (infusion). Careful measures are in place throughout this process to ensure safe, high-quality services.
Here’s more about how it works:
T Cell Collection
We remove blood through a needle in your arm. The blood flows into an apheresis machine, which removes specific blood components (like T cells). The remaining components flow back into your body through a needle in the other arm.
Infusion
When the modified cells are ready, we admit you to the hospital and deliver them via infusion. Before receiving CAR T cells, you undergo a few days of chemotherapy followed by a few days of rest. You then receive a blood transfusion containing your T cells.
Monitoring
It’s necessary to stay in the hospital after CAR T-cell therapy so we can monitor your response. You may receive medications to prevent or control side effects, such as reactions to CAR T-cells (cytokine release syndrome), infections or fever. Monitoring may last a few days or up to several weeks.
CAR T-Cell Therapy: Why Choose Us?
Expertise
You receive services from hematologist-oncologists who deliver the best available blood cancer treatments. Our depth of experience with CAR T-cell therapy leads to timely, appropriate care. Our attentive approach makes it possible to manage side effects so you can achieve excellent results.
CAR-T Cell Therapy Research
UMass Memorial is one of the few programs in the region advancing blood cancer treatment through research. We participate in regional and national clinical trials exploring CAR T-cell therapy’s effectiveness for additional cancer types. Find out more about cancer research and clinical trials.
Coordinated Care
CAR T-cell therapy is one of many services that make up your personalized care plan. Hematologist-oncologists may arrange additional treatments before or after CAR T-cell therapy. We also offer comprehensive support from nurse navigators, social workers and palliative medicine doctors. Get more information about cancer resources and support.
Get Started
Call 855-UMASS-MD (855-862-7763) to make an appointment with a CAR T-cell therapy.